Protein Purification
MilliporeSigma™ Calbiochem™ Eg5 Inhibitor III, Dimethylenastron
The Eg5 Inhibitor III, Dimethylenastron, also referenced under CAS 863774-58-7, controls the biological activity of Eg5. This small molecule/inhibitor is primarily used for Membrane applications.
MilliporeSigma™ Calbiochem™ AKR1C1 Inhibitor, 5-PBSA
The AKR1C1 Inhibitor, 5-PBSA, also referenced under CAS 4906-68-7, controls the biological activity of AKR1C1.
MilliporeSigma™ Calbiochem™ PD 169316
A potent, cell-permeable, reversible, competitive, and selective p38 MAP kinase inhibitor (IC50 = 89 nM).
MilliporeSigma™ Calbiochem™ Riluzole
A cell-permeable benzothiazole compound that potently inhibits glutamate release and blocks Na+ channels.
MilliporeSigma™ Calbiochem™ Protein Lysine Methyltransferase Inhibitor, UNC0321
A cell-permeable, quinazoline analog that potently and selectively inhibits PKMT G9a (IC50 = 6nM and 9nM in two biochemical assays for CLOT and ECSD, respectively, and Ki = 63 pM, which is approximately 250-fold more potent than a closely-related analog, BIX0129
MilliporeSigma™ Calbiochem™ InSolution™ NF-κB Activation Inhibitor
The InSolution™ NF-κB Activation Inhibitor controls the biological activity of NF-κB. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
MilliporeSigma™ Calbiochem™ Adenosine 3',5'-cyclic Monophosphorothioate, Rp-Isomer, Triethylammonium Salt
A cell-permeable and reversible inhibitor of protein kinase A (Ki = 11 μM).
MilliporeSigma™ Calbiochem™ PDGFR Tyrosine Kinase Inhibitor V
The PDGFR Tyrosine Kinase Inhibitor V, also referenced under CAS 347155-76-4, controls the biological activity of PDGFR Tyrosine Kinase. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Cyclopamine, V. californicum
Cyclopamine, V. californicum, CAS 4449-51-8, is a cell-permeable steroidal alkaloid & cholesterol mimic that specifically antagonizes Sonic Hedgehog signaling through direct interaction with Smo.
MilliporeSigma™ Calbiochem™ β-Catenin/Tcf Inhibitor III, iCRT3
The β-Catenin/Tcf Inhibitor III, iCRT3 controls the biological activity of β-Catenin/Tcf. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ Caspase-9 Substrate II, Colorimetric
The Caspase-9 Substrate II, Colorimetric serves as the substrate for Caspase-9.
MilliporeSigma™ Calbiochem™ VEGF Inducer, GS4012
A cell-permeable pyridinyl-thioether compound that acts as a potent inducer of VEGF and VEGF-mediated vessel formation.
MilliporeSigma™ Calbiochem™ Bcl-2 Binding Peptide, Cell-Permeable, Negative Control
A cell-permeable, mutated cpm-1285 peptide analog (Leu151 replaced by Ala) that does not induce apoptosis and displays nearly 15-fold reduction in Bcl-2 binding.
MilliporeSigma™ Calbiochem™ EPAC Inhibitor, ESI-09
A cell-permeable compound that targets cAMP-binding domain of EPAC/cAMP-GEF and inhibits cAMP-dependent EPAC GEF activity (IC50 = 1.4 and 3.2 μM, respectively, against EPAC2 and EPAC1).
MilliporeSigma™ Calbiochem™ InSolution™ KN-92
Negative Control