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A cell-permeable hydrazone compound that reversibly binds eukaryotic translation initiation factor 4E (eIF4E; KD = 25μM) and disrupts eIF4E/eIF4G, but not eIF4E/4E-BP1, complex format
The IKK-2 Inhibitor V, also referenced under CAS 978-62-1, controls the biological activity of IKK-2. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
Thermo Scientific™ CaptureSelect™ AAT-XL Affinity Matrix has been specifically designed for the purification of native human alpha-1 antitrypsin (AAT) from complex sources like plasma/serum and recombinant human AAT from cell culture supernatants.
The Nitric Oxide Synthase, Neuronal Inhibitor I, also referenced under CAS 357965-99-2, controls the biological activity of neuronal Nitric Oxide Synthase. This small molecule/inhibitor is primarily used for Inflammation/Immunology applications.
A cell-permeable phenylimidazopyridinyl-methoxy coumarin compound that inhibits caspase-3 and caspase-6 activities (IC50 = 35 and 38μM, respectively) by targeting both the large and small subunit active si
The DNA-PK Inhibitor, also referenced under CAS 20357-25-9, controls the biological activity of DNA-PK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
The PKCθ Pseudosubstrate Inhibitor, Myristoylated controls the biological activity of PKCθ. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
Desthiobiotin-ATP and -ADP probes to label, affinity purify and measure the active site of ATPases (kinases), including chaperones and metabolic enzymes.
ActivX™ probes have been designed to selectively label and enrich kinases through binding of their respective active sites with desthiobiotin tagged ATP or ADP to enable assessment of enzyme activity.